Using a University of Pennsylvania-designed device to noninvasively and continuously monitor cerebral blood flow (CBF) in acute stroke patients, researchers from Penn Medicine and the Department of Physics & Astronomy in Penn Arts and Sciences are now learning how head of bed (HOB) positioning affects blood flow reaching the brain. Most patients admitted to the hospital with an acute stroke are kept flat for at least 24 hours in an effort to increase CBF in vulnerable brain regions surrounding the damaged tissue. Researchers report in the journal Stroke that, while flat HOB did indeed increase CBF in the damaged hemisphere in most stroke patients, about one quarter of the patients had a paradoxical response and showed the highest CBF with their head at an elevated angle.
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