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Psoriasis researchers identify molecular changes responsible for skin discoloration

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(Medical Xpress)—Itchy, painful rashes—such as those that occur with psoriasis—are uncomfortable, but at least they fade when the flare-up subsides. Mostly. Evidence often remains in the form of dark, discolored areas of skin, serving as a reminder of the disease. A new study supported by the Milstein Medical Research Program at The Rockefeller University, however, has uncovered the molecular roots of skin discoloration that is often associated with psoriasis, suggesting the possibility of new treatments for pigmentation changes seen not only in psoriasis, but also in other conditions such as eczema and acne.

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